Reduction of cholera in Bangladeshi villages by simple filtration
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Colwell, Rita R.
Islam, M. Sirajul
Khan, N. Huda
Sack, R. Bradley
Sack, David A.
Abstract Based on results of ecological studies demonstrating that Vibrio cholerae, the etiological agent of epidemic cholera, is commensal to zooplankton, notably copepods, a simple filtration procedure was developed whereby zooplankton, most phytoplankton, and particulates >20 microm were removed from water before use. Effective deployment of this filtration procedure, from September 1999 through July 2002 in 65 villages of rural Bangladesh, of which the total population for the entire study comprised approximately 133,000 individuals, yielded a 48% reduction in cholera (P < 0.005) compared with the control
Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1051-5