Detection of antibodies to toxin-coregulated pili in sera from cholera patients

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dc.contributor.authorAttridge, Stephen R.-
dc.contributor.authorWallerström, Gun-
dc.contributor.authorQadri, Firdausi-
dc.contributor.authorSvennerholm, Ann-Mari-
dc.date.accessioned2015-03-11T06:54:14Z-
dc.date.available2015-03-11T06:54:14Z-
dc.date.issued2004-03-
dc.identifier.citationInfect Immun 2004 Mar;72(3):1824-7en
dc.identifier.urihttp://hdl.handle.net/123456789/5684-
dc.description.abstractAbstract Monoclonal antibodies (MAbs) were prepared against toxin-coregulated pili (TCP) isolated from Vibrio cholerae O1 El Tor. Despite their limited bactericidal potential, two MAbs were able to mediate biotype-specific protection against experimental cholera in infant mice. These MAbs were used in immunoblotting studies to assess seroconversion to El Tor TCP following cholera. Clear anti-pilus responses were observed in five of nine patients.en
dc.format.extent85764 bytes-
dc.format.mimetypeapplication/pdf-
dc.language.isoenen
dc.subjectAntibodiesen
dc.subjectCholeraen
dc.subjectBacterial toxinsen
dc.titleDetection of antibodies to toxin-coregulated pili in sera from cholera patientsen
dc.typeArticleen
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