Oral maintenance therapy for cholera patients in all age groups

Full metadata record
DC FieldValueLanguage
dc.contributor.authorNalin, David R.-
dc.contributor.authorCash, Richard A,-
dc.contributor.authorRahman, Mizanur-
dc.date.accessioned2007-12-11T07:59:47Z-
dc.date.available2007-12-11T07:59:47Z-
dc.date.issued1970-
dc.identifier.citationBull World Health Organ 1970;43(3):361-3-
dc.identifier.urihttp://hdl.handle.net/123456789/451-
dc.description.abstract56 children and 50 adults were studied to determine the effectiveness of an oral (or nasogastric) therapy with a glucose-electrolyte solution for treating cholera patients. The development of this inexpensive regimen is described. The therapy has the advantages of being cheap, not requiring sterile conditions, and having wide availability in endemic areas. The oral solution contained the following ions (as milliequivalents per liter of water): Na+, 120 K+, 25; CO2-, 48; CL-, 97; and glucose at 110 mmol/liter. Patients received nothing orally except the solution and a 5-day course of tetracycline (dosed according to body weight). The oral (or nasogastric) therapy was used as a supplement when patients arrived in shock, at which time intravenous infusion was used to begin rehydration; patients with milder cholera cases were given only the oral therapy, with much success. All children were maintained in a positive balance with the oral (or nasogastric) solution after correction of shock by intravenous rehydration, and the mean volume of oral solution required by the 56 children was 6 liters. In field trials, 80% of the patients were in positive net intestinal balance by 6 hours after initiation of oral therapy. Adults studied to determine in the 25 mEq potassium/liter solution was safe showed that after administration adult plasma potassium levels were normal.en
dc.format.extent139285 bytes-
dc.format.mimetypeapplication/pdf-
dc.language.isoenen
dc.subjectOral Therapyen
dc.subjectCholeraen
dc.subjectCholera-fluid therapyen
dc.subjectCholera-epidemilogyen
dc.titleOral maintenance therapy for cholera patients in all age groupsen
dc.typeArticleen
Appears in Collections:A. Original papers

Files in This Item:
File Description SizeFormat 
1970-BullWorldHealthOrgan-361-NalinDR.pdf136.02 kBAdobe PDFView/Open    Request a copy


This item is protected by original copyright