Non-immunological defence mechanisms of the gut

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dc.contributor.authorSarker, S.A.-
dc.contributor.authorGyr, K.-
dc.date.accessioned2013-10-09T02:50:00Z-
dc.date.available2013-10-09T02:50:00Z-
dc.date.issued1992-
dc.identifier.citationGut 1992 Jul;33(7):987-93en
dc.identifier.urihttp://hdl.handle.net/123456789/4496-
dc.description.abstractNon-immunological defence mechanisms represent an important line of intestinal defence in addition to humoral and cellular immunity. This review summarises the evidence for the role of the non-immunological defence system. Protective factors that have been amply documented are gastric juice, intestinal motility, and intestinal flora. Components of pancreatic juice, lysozyme, and epithelial cell turnover may also be involved. Special attention is given to gastric acid, infection with Helicobacter pylori, and hypochlorhydria and their association with infectious diarrhoea. Epidemic hypochlorhydria is discussed since this increases sensitivity to intestinal infections in third world countriesen
dc.format.extent1508983 bytes-
dc.format.mimetypeapplication/pdf-
dc.language.isoenen
dc.subjectBacterial Infectionsen
dc.subjectGastric Juiceen
dc.subjectGastrointestinal Motilityen
dc.subjectIntestinal Diseasesen
dc.subjectIntestinesen
dc.subjectAchlorhydriaen
dc.titleNon-immunological defence mechanisms of the guten
dc.typeArticleen
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