Crossed immunoelectrophoretic analysis of antigenic composition of B-subunit/whole-cell and whole-cell only killed oral cholera vaccines

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dc.contributor.authorCiznár, I.-
dc.contributor.authorAhsan, C.R.-
dc.contributor.authorRahman, A.-
dc.contributor.authorShahabuddin, M.-
dc.contributor.authorBartková, G.-
dc.contributor.authorClemens, J.D.-
dc.contributor.authorSack, D.A.-
dc.date.accessioned2013-09-15T04:54:54Z-
dc.date.available2013-09-15T04:54:54Z-
dc.date.issued1992-
dc.identifier.citationVaccine 1992;10(9):591-6en
dc.identifier.urihttp://hdl.handle.net/123456789/4451-
dc.description.abstractCrossed immunoelectrophoresis was used to identify antigens preserved in the whole-cell component of oral cholera vaccines tested in the field trial in Bangladesh. The composition and immunogenicity of the vaccine antigens were compared with those of antigens obtained from live cells of Vibrio cholerae 01 of both biovars and serovars. The whole-cell component of the vaccine contained ten antigens in comparison with the live Vibrio cells which revealed the presence of 30 antigens. The whole-cell component contained lipopolysaccharide, flagellar antigen, one cell-bound haemagglutinin and at least six outer membrane protein antigensen
dc.format.extent612067 bytes-
dc.format.mimetypeapplication/pdf-
dc.language.isoenen
dc.subjectCholera Vaccinesen
dc.subjectHemagglutinins-isolation & purificationen
dc.subjectImmunoelectrophoresis, Two-Dimensionalen
dc.subjectLipopolysaccharides/en
dc.subjectRabbitsen
dc.subjectVaccines, Inactivateden
dc.subjectVibrio choleraeen
dc.subjectAnimalsen
dc.subjectAdministration, Oralen
dc.titleCrossed immunoelectrophoretic analysis of antigenic composition of B-subunit/whole-cell and whole-cell only killed oral cholera vaccinesen
dc.typeArticleen
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