Formation and selection of intergenogroup reassortants during cell culture adaptation of rotaviruses from dually infected subjects

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dc.contributor.authorWard, Richard L.-
dc.contributor.authorNakagomi, Osamu-
dc.contributor.authorKnowlton, Douglas R.-
dc.contributor.authorMcNeal, Monica M.-
dc.contributor.authorNakagomi, Toyoko-
dc.contributor.authorHuda, Nurul-
dc.contributor.authorClemens, John D.-
dc.contributor.authorSack, David A.-
dc.date.accessioned2013-08-28T06:26:18Z-
dc.date.available2013-08-28T06:26:18Z-
dc.date.issued1991-
dc.identifier.citationJ Virol 1991 May;65(5):2699-701en
dc.identifier.urihttp://hdl.handle.net/123456789/4425-
dc.description.abstractA previous study showed that intergenogroup reassortants of human rotaviruses can persist in nature (R.L. Ward, O. Nakagomi, D.R. Knowlton, M.M. McNeal, T. Nakagomi, J.D. Clemens, D.A. Sack, and G.M. Schiff, J. Virol. 64:3219-3225, 1990), but the mechanisms involved in their formation and selection had not been determined. In this study it was shown that, during cell culture adaptation of rotaviruses belonging to different genogroups from stools of dually infected subjects, intergenogroup reassortants were formed and selected, presumably mimicking the processes that occur in natureen
dc.format.extent1062725 bytes-
dc.format.mimetypeapplication/pdf-
dc.language.isoenen
dc.subjectRotavirusen
dc.subjectRotavirus Infections-immunologyen
dc.subjectRNA, Viralen
dc.subjectAntibodies, Viralen
dc.subjectCells, Cultureden
dc.titleFormation and selection of intergenogroup reassortants during cell culture adaptation of rotaviruses from dually infected subjectsen
dc.typeArticleen
Appears in Collections:A. Original papers

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