Therapeutic efficasy of artemether-lumefantrine
Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Haque, Rashidul | - |
| dc.contributor.author | Thriemer, Kamala | - |
| dc.date.accessioned | 2007-11-25T04:20:14Z | - |
| dc.date.available | 2007-11-25T04:20:14Z | - |
| dc.date.issued | 2007-11-25T04:20:14Z | - |
| dc.identifier.uri | http://hdl.handle.net/123456789/390 | - |
| dc.description | Short report | en |
| dc.description.abstract | Bangladesh faces increasing levels of chloroquine resistance, and drug sensitivity to sulfadoxinepyremethamine is already compromised. Therefore, the Ministry of Health recently changed the national treatment guidelines to artemisinin-based combination therapies. The purpose of this study was to determine the baseline therapeutic efficacy of artemether-lumefantrine used as a six-dose regimen for the treatment of uncomplicated Plasmodium falciparum malaria. Sixty-seven patients were enrolled in the study; the cure rate in a 42-day follow-up after an adjustment by polymerase chain reaction was 94.3%. The treatment led to rapid fever (mean ± SD 25.82 ± 12.14 hours) and parasite (30.36 ± 19.43 hours) clearance. These data suggest that artemether-lumefantrine is a highly efficacious and well-tolerated treatment for uncomplicated P. falciparum malaria in Bangladesh. | en |
| dc.description.sponsorship | The study was supported by the United States Department of Defense Global Emerging Infections System program and the Austrian Science Fund (project no. 15754-B02). | en |
| dc.format.extent | 54106 bytes | - |
| dc.format.mimetype | application/pdf | - |
| dc.language.iso | en_US | en |
| dc.subject | Plasmodium Falciparum | en |
| dc.title | Therapeutic efficasy of artemether-lumefantrine | en |
| dc.type | Article | en |
| Appears in Collections: | A. Original papers | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Haque R_Am J Trop Med Hyg_Jan07.pdf | 52.84 kB | Adobe PDF | View/Open Request a copy |
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