Hepatitis B infection in Bangladeshi mothers and infants

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dc.contributor.authorde Francisco, A.-
dc.contributor.authorHall, A.J.-
dc.contributor.authorAlam, N.-
dc.contributor.authorHawkes, S.-
dc.contributor.authorAzim, T.-
dc.identifier.citationSoutheast Asian J Trop Med Public Health 1999 Jun;30(2):296-8en
dc.description.abstractIn order to estimate the relative importance of perinatal transmission of hepatitis B in rural Bangladesh a cross-sectional study was carried out. Paired-serum samples of infants aged 2-8 months old, a group of new born, and their mothers were tested for hepatitis B markers using a commercial ELISA test kit. In total, 107 (32.4%) positive for HBcAg, 18 (5.4%) for HBsAg, and 4 (1.2%) for HbeAg. Of the infants, 35 (10.5%) positive for HBcAg, 1 (0.3%) for HBsAg, and none for HBeAg. Of the 18 HBsAg positive mothers, 4 (22%) were HBeAg positive. All 14 children of mothers who were HBeAg negative were negative for HBsAg. Only one out of four (25%) of children of HBeAg positive mothers were HBsAg carriers (8 months old), and in three children transmission did not occur (two 8 months, one 6 months old). This survey indicates that hepatitis B is prevalent in rural Bangladesh and that the perinatal transmission mode may be relatively lowen
dc.format.extent83412 bytes-
dc.subjectCross-sectional studiesen
dc.subjectHepatitis Ben
dc.subjectHepatitis B surface antigensen
dc.titleHepatitis B infection in Bangladeshi mothers and infantsen
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