Monoclonal antibodies specific for the bundle-forming pilus of enteropathogenic Escherichia coli[short note]

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dc.contributor.authorGirón, Jorge A.-
dc.contributor.authorQadri, F.-
dc.contributor.authorAzim, T.-
dc.contributor.authorJarvis, K.J.-
dc.contributor.authorKaper, J.B.-
dc.contributor.authorAlbert, M.J.-
dc.date.accessioned2008-10-28-
dc.date.available2008-10-28-
dc.date.issued1995-
dc.identifier.citationInfect Immun 1995 Dec;63(12):4949-52en
dc.identifier.urihttp://hdl.handle.net/123456789/1945-
dc.description.abstractThe bundle-forming pilus (BFP) produced by enteropathogenic Escherichia coli (EPEC) is associated with the presence of a large EPEC adherence factor plasmid and the formation of localized adherence clusters on tissue culture cells. Three mouse monoclonal antibodies (ICA2, ICA3, and ICA4) were produced against BFP purified from EPEC B171 (O111:NM). These monoclonal antibodies reacted in immunoblots with different epitopes of the 19.5-kDa bundlin subunit of BFP of heterologous EPEC. These reagents could serve as diagnostic tools for the identification of EPEC as well as for studying the role of BfpA in the interaction of EPEC with eukaryotic cellsen
dc.format.extent298569 bytes-
dc.format.mimetypeapplication/pdf-
dc.language.isoenen
dc.subjectEscherichia coli-Enteropathogenicen
dc.subjectAntibodies, Monoclonalen
dc.subjectDiarrheaen
dc.titleMonoclonal antibodies specific for the bundle-forming pilus of enteropathogenic Escherichia coli[short note]en
dc.typeArticleen
Appears in Collections:A. Original papers

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