A. Original papers
5332 publications available
Heterogeneity in the organization of the CTX genetic element in strains of Vibrio cholerae O139 Bengal isolated from Calcutta, India and Dhaka, Bangladesh and its possible link to the dissimilar incidence of O139 cholera in the two localesAfter a lapse of 33 months, Vibrio cholerae O139, the new serogroup associated with cholera, has re-emerged in Calcutta, India and has become the dominant serogroup causing cholera from September 1996. In neighbouring Bangladesh,...
The acidosis of cholera. Contributions of hyperproteinemia, lactic acidemia, and hyperphosphatemia to an increased serum anion gapTo study the metabolic acidosis that occurs during the diarrhea of cholera, we examined the serum anion gap in 21 patients with hypovolemic shock due to Vibrio cholerae infection. Measurements of serum electrolytes, as well...
Development of Immunoglobulin M memory to both a T cell-independent and a T cell-dependent antigen following infection with Vibrio cholerae O1 in BangladeshVibrio cholerae O1 can cause severe watery diarrhea that can be life-threatening without treatment. Infection results in long-lasting protection against subsequent disease. Development of memory B cells of the immunoglobulin G (IgG) and&...
Water management practices in rural and urban homes: a case study from Bangladesh on ingestion of polluted waterAlthough Bangladesh has achieved remarkable success in extending the availability of hand pumped and piped water, unsafe water is still ingested. This brief study attempted to assess water management practices in rural and urban...
Occurrence and expression of luminescence in Vibrio choleraeSeveral species of the genus Vibrio, including Vibrio cholerae, are bioluminescent or contain bioluminescent strains. Previous studies have reported that only 10% of V. cholerae strains are luminescent. Analysis of 224 isolates of n...
Therapeutic efficasy of artemether-lumefantrineBangladesh faces increasing levels of chloroquine resistance, and drug sensitivity to sulfadoxinepyremethamine is already compromised. Therefore, the Ministry of Health recently changed the national treatment guidelines to artemisinin-based comb...
Isolation of Escherichia coli bacteriophages from the stool of pediatric diarrhea patients in Bangladesh.Abstract A 3-week coliphage survey was conducted in stool samples from 140 Bangladeshi children hospitalized with severe diarrhea. On the Escherichia coli indicator strain K803, all but one phage isolate had 170-kb genomes and...
Zinc therapy for diarrhoea increased the use of oral rehydration therapy and reduced the use of antibiotics in Bangladeshi childrenAbstract Excessive use of antibiotics for diarrhoea is a major contributing factor towards increasing rates of antimicrobial resistance in developing countries. Zinc therapy for diarrhoea has been shown to be beneficial in...
Iron and zinc supplementation promote motor development and exploratory behavior among Bangladeshi infantsAbstract BACKGROUND: Iron and zinc deficiency are prevalent during infancy in low-income countries. OBJECTIVES: The objectives were to examine whether a weekly supplement of iron, zinc, iron+zinc, or a mi...
Integrated Management of Childhood Illness (IMCI) in Bangladesh: early findings from a cluster-randomised studyAbstract BACKGROUND: We report the preliminary findings from a continuing cluster randomised evaluation of the Integrated Management of Childhood Illness (IMCI) strategy in Bangladesh. METHODS: 20 first-level outpa...
The major subunit of the toxin-coregulated pilus TcpA induces mucosal and systemic immunoglobulin A immune responses in patients with cholera caused by Vibrio cholerae O1 and O139Abstract Diarrhea caused by Vibrio cholerae is known to give long-lasting protection against subsequent life-threatening illness. The serum vibriocidal antibody response has been well studied and has been shown to correlate ...
Detection of endotoxin in sera from children hospitalized for treatment of diarrhea in BangladeshAbstract The level of circulating endotoxin was determined in the sera from children hospitalized for treatment of diarrhea at the International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh. A significant level ...
Violent deaths among women of reproductive age in rural BangladeshAbstract The objectives of this paper are to investigate levels and trends in mortality due to violence in women of reproductive age and the social and demographic factors associated with such mortality. The study&...
Cultural and social context of dysentery: implications for the introduction of a new vaccine.Abstract Dysentery, a severe form of diarrhoeal disease, is a major cause of morbidity and mortality. Paradoxically, virtually no studies have been conducted to examine beliefs and behaviours associated with dysentery. The...
Visceral leishmaniasis: consequences to women in a Bangladeshi communityAbstract Visceral leishmaniasis (VL) or kala-azar (KA) affects the rural poor, causing significant morbidity and mortality. We examined the epidemiological and social impact of KA in an affected village in Bangladesh. A ...
Assessment of evolution of pandemic Vibrio parahaemolyticus by multilocus sequence typingAbstract The genetic relatedness of 81 isolates of Vibrio parahaemolyticus was assessed by multilocus sequence typing. The strain with serotype O3:K6 emerged as a pandemic pathogen in 1996, with subsequent expansion to include ...
Detection of antibodies to toxin-coregulated pili in sera from cholera patientsAbstract Monoclonal antibodies (MAbs) were prepared against toxin-coregulated pili (TCP) isolated from Vibrio cholerae O1 El Tor. Despite their limited bactericidal potential, two MAbs were able to mediate biotype-specific protection&...
Publications in this collection
- Yunus, M. 39
- Sack, R. Bradley 38
- Aziz, K.M.A. 36
- Wahed, M.A. 35
- Huq, M.I. 34
- Nair, G. Balakrish 34
- Aziz, K.M.S. 33
- Albert, M.J. 32
- Butler, Thomas 32
- Islam, M.S. 32
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- Cholera 264
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- Diarrhea, Infantile 163
- Diarrhea 109
- Dysentery, Bacillary 108
- Humans 72
- Child, Preschool 71
- Shigella dysenteriae 64
- Diarrheal diseases 61
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