Weak serum and intestinal antibody responses to Vibrio cholerae soluble hemagglutinin in cholera patients

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dc.contributor.authorSvennerholm, Ann-Mari-
dc.contributor.authorLevine, Myron M.-
dc.contributor.authorHolmgren, Jan-
dc.date.accessioned2008-07-07T03:44:57Z-
dc.date.available2008-07-07T03:44:57Z-
dc.date.issued1984-09-
dc.identifier.citationInfect Immun 1984 Sep;45(3):792-4en
dc.identifier.urihttp://hdl.handle.net/123456789/1422-
dc.description.abstractA soluble hemagglutinin/protease from Vibrio cholerae has been suggested to be a putative virulence factor and protective antigen. However, clinical cholera infection gave rise to detectable serum antibody responses to soluble hemagglutinin in only 2 of 10 Bangladeshi patients or 1 of 17 cholera-infected North American volunteers. A gut mucosal immunoglobulin A antibody response to soluble hemagglutinin was seen in 4 of 8 Bangladeshi patients, but in 0 of 10 North American volunteers. These responses were much weaker than those to cholera toxin or lipopolysaccharideen
dc.format.extent198347 bytes-
dc.format.mimetypeapplication/pdf-
dc.language.isoenen
dc.subjectVibrio choleraen
dc.subjectAntibodies reactionen
dc.subjectCholera infectionen
dc.subjectHemagglutininen
dc.titleWeak serum and intestinal antibody responses to Vibrio cholerae soluble hemagglutinin in cholera patientsen
dc.typeArticleen
Appears in Collections:A. Original papers

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