DSpace About icddr,b  

DSpace at icddr,b >
Clinical Sciences >
Clinical sciences research papers >


Title: Disease due to enterotoxigenic Escherichia coli in Bangladeshi adults: clinical aspects and a controlled trial of tetracycline
Authors: Merson, M.H.
Sack, R.B.
Islam, S.
Saklayen, G.
Huda, N.
Huq, I.
Zulich, A.W.
Yolken, R.H.
Kapikian, A.Z.
Keywords: Escherichia coli, Enterotoxigenic
Diarrhea-drug therapy
Issue Date: Jun-1980
Citation: J Infect Dis 1980 Jun;141(6):702-11
Abstract: The clinical characteristics of disease due to enterotoxigenic Escherichia coli (ETEC) were determined in 88 adult males admitted to a hospital in Dacca, Bangladesh, with moderate to severe dehydration. Persons infected with ETEC strains producing both heat-labile toxin (LT) and heat-stable (ST) toxin had more dehydration and acidosis, longer duration of illness, and greater stool volume than persons infected with strains producing only ST. Tetracycline therapy, evaluated in 63 cases, resulted in slightly earlier termination of illness in patients with LT-ST strains but had no effect on illness in the patients with ST strains. In both groups of patients tetracycline shortened the duration of excretion of organisms. Because of its limited effectiveness and the generally excellent response of ETEC diarrhea to rehydration therapy alone, tetracycline is not warranted for use in treatment of ETEC diarrhea in adults in this population
URI: http://hdl.handle.net/123456789/602
Appears in Collections:Clinical sciences research papers

Files in This Item:

File Description SizeFormat
1980-JInfectDis-702-MersonMH.pdf431KbAdobe PDFView/Open

This item is protected by original copyright

All items in DSpace are protected by copyright, with all rights reserved.


Valid XHTML 1.0! DSpace Software Copyright © 2002-2006 MIT and Hewlett-Packard - Feedback